Jordi Tamarit Sumalla
Grau: Doctor/a
973 702 475
jordi.tamarit(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/C-6316-2008
Publicacions
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Sanz-Alcázar A; Britti E; Delaspre F; Medina-Carbonero M; Pazos-Gil M; Tamarit J; Ros J; Cabiscol E
Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models.
Cellular And Molecular Life Sciences 81 12-12. .
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Alves, R; Pazos-Gil, M; Medina-Carbonero, M; Sanz-Alcazar, A; Delaspre, F; Tamarit, J
Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 -. .
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Medina-Carbonero, M; Sanz-Alcazar, A; Britti, E; Delaspre, F; Cabiscol, E; Ros, J; Tamarit, J
Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations.
Cellular And Molecular Life Sciences 79 74-74. .
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Tamarit J; Britti E; Delaspre F; Medina-Carbonero M; Sanz-Alcázar A; Cabiscol E; Ros J
Mitochondrial iron and calcium homeostasis in Friedreich ataxia.
IUBMB LIFE 73 543-553. .
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Britti E; Delaspre F; Sanz A; Medina-Carbonero M; Llovera M; Purroy R; Mincheva-Tasheva S; Tamarit J; Ros J
Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia.
BIOCHEMICAL JOURNAL 478 1-20. .
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Britti, E; Delaspre, F; Tamarit, J; Ros, J
Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na + /Ca 2+ Exchanger, NCLX, and Apoptosis.
NEUROCHEMICAL RESEARCH 46 108-119. .
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Rodríguez-Pascau L; Britti E; Calap-Quintana P; Dong YN; Vergara C; Delaspre F; Medina M; Tamarit J; Pallardó FV; Gonzalez-Cabo P; Ros J; Lynch DR; Martinell M; Pizcueta P
PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia.
NEUROBIOLOGY OF DISEASE 148 105162-105162. .
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Purroy, R; Medina-Carbonero, M; Ros, J; Tamarit, J
Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase.
Redox Biology 32 101520-101520. .
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Britti, Elena; Delaspre, Fabien; Tamarit, Jordi; Ros, Joaquim
Mitochondrial calcium signalling and neurodegenerative diseases
Neuronal Signaling 2 20180061-20180061. .
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Alsina, D; Purroy, R; Ros, J; Tamarit, J
Iron in Friedreich Ataxia: A Central Role in the Pathophysiology or an Epiphenomenon?
PHARMACEUTICALS 11 -. .
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Britti, E; Delaspre, F; Mincheva, S; Llovera, M; Tamarit, J; Ros, J
Calcitriol as a supplement for Friedreich ataxia
FEBS Open Bio 8 213-213. .
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Lledos, RP; Ros, J; Tamarit, J
Alterations in mitochondrial multimeric dehydrogenase complexes in a cardiac model of Friedreich ataxia
FEBS Open Bio 8 91-92. .
Projectes
- Uncovering the function of a conserved site in eukaryotic frataxins.
- Mecanismos de disfuncion mitocondrial y nuevas estrategias terapéuticas en modelos celulares y animales de Ataxia de Friedreich
- Nuevo fármaco dirigido a la Ataxia de Friedreich
- Targeting mitochondria in Friedreich Ataxia: molecular mechanisms and therapeutic approaches
- MODELOS CELULARES DE ATAXIA DE FRIEDREICH: BASES MOLECULARES DE LA PATOLOGIA E IDENTIFICACION DE BIOMARCADORES Y COMPUESTOS CON POTENCIAL TERAPEUTICO
- Modelos celulares de ataxia de Friedreich: bases moleculares de la patología e identificación de biomarcadores y compuestos con potencial terapéutico
- PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES
- Papel funcional del estrés oxidativo y nitrosativo en grandes sistemas biológicos.
- Estrés oxidativo, envejecimiento celular, homeostasis del hierro y patologías relacionadas en S. cerevisae como modelo celular
