Directori de persones
Rosa Maria Soler Tatche

Rosa Maria Soler Tatche

Grau: Doctor/a

973 702 264
rosa.soler(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7361-2010

Publicacions

  • Gou-Fabregas M; Ramírez-Núñez O; Cacabelos D; Bahi N; Portero M; Garcera A; Soler RM

    Calpain activation and CaMKIV reduction in spinal cords from hSOD1G93A mouse model

    MOLECULAR AND CELLULAR NEUROSCIENCE 61 219-225. .

    [doi:10.1016/j.mcn.2014.07.002]

  • Garcera A; Bahi N; Periyakaruppiah A; Arumugam S; Soler RM

    Survival motor neuron protein reduction deregulates autophagy in spinal cord motoneurons in vitro

    CELL DEATH & DISEASE 4 -. .

    [doi:10.1038/cddis.2013.209]

  • Caraballo-Miralles, Victor; Cardona-Rossinyol, Andrea; Garcera, Ana; Torres-Benito, Laura; Soler, Rosa M.; Tabares, Luca; Llado, Jeronia; Olmos, Gabriel

    Notch Signaling Pathway Is Activated in Motoneurons of Spinal Muscular Atrophy

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 14 11424-11437. .

    [doi:10.3390/ijms140611424]

  • Mincheva-Tasheva S; Soler RM

    NF-kappa B Signaling Pathways: Role in Nervous System Physiology and Pathology

    NEUROSCIENTIST 19 175-194. .

    [doi:10.1177/1073858412444007]

  • Caraballo-Miralles, Victor; Cardona-Rossinyol, Andrea; Garcera, Ana; Villalonga, Priam; Soler, Rosa M.; Olmos, Gabriel; Llado, Jeronia

    SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA

    MOLECULAR AND CELLULAR NEUROSCIENCE 49 282-289. .

    [doi:10.1016/j.mcn.2011.12.003]

  • Garcera, Ana; Mincheva, Stefka; Gou-Fabregas, Myriam; Caraballo-Miralles, Victor; Llado, Jeronia; Comella, Joan X.; Soler, Rosa M.

    A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons.

    NEUROBIOLOGY OF DISEASE 42 415-426. .

    [doi:10.1016/j.nbd.2011.02.003]

  • Mincheva, Stefka; Garcera, Ana; Gou-Fabregas, Myriam; Encinas, Mario; Dolcet, Xavier; Soler, Rosa M.

    The canonical nuclear factor-?B pathway regulates cell survival in a developmental model of spinal cord motoneurons.

    JOURNAL OF NEUROSCIENCE 31 6493-6503. .

    [doi:10.1523/JNEUROSCI.0206-11.2011]

  • Moubarak, Rana S.; Sole, Carme; Pascual, Marta; Gutierrez, Humberto; Llovera, Marta; Jose Perez-Garcia, M.; Gozzelino, Raffaella; Segura, Miguel F.; Iglesias-Guimarais, Victoria; Reix, Stephanie; Soler, Rosa M.; Davies, Alun M.; Soriano, Eduardo; Yuste, Victor J.; Comella, Joan X.

    The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

    JOURNAL OF NEUROSCIENCE 30 6094-6105. .

    [doi:10.1523/JNEUROSCI.0537-10.2010]

  • Mir, M.; Asensio, V. J.; Tolosa, L.; Gou-Fabregas, M.; Soler, R. M.; Llado, J.; Olmos, G.

    Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants.

    NEUROSCIENCE 162 959-971. .

    [doi:10.1016/j.neuroscience.2009.05.049]

  • Gou-Fabregas, Myriam; Garcera, Ana; Mincheva, Stefka; Jose Perez-Garcia, M.; Comella, Joan X.; Soler, Rosa M.

    Specific vulnerability of mouse spinal cord motoneurons to membrane depolarization.

    JOURNAL OF NEUROCHEMISTRY 110 1842-1854. .

    [doi:10.1111/j.1471-4159.2009.06278.x]

  • Perez-Garcia, M. Jose; Gou-Fabregas, Myriam; de Pablo, Yolanda; Llovera, Marta; Comella, Joan X.; Soler, Rosa M.

    Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV.

    Journal Of Biological Chemistry 283 4133-4144. .

    [doi:10.1074/jbc.M705477200]

  • de Pablo, Yolanda; Perez-Garcia, M. Jose; Georgieva, Maya V.; Sanchis, Daniel; Lindqvist, Niclas; Soler, Rosa M.; Comellal, Joan X.; Lloveral, Marta

    Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.

    JOURNAL OF NEUROCHEMISTRY 104 124-139. .

    [doi:10.1111/j.1471-4159.2007.05027.x]

Projectes

  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • Analysis of the beneficial effects of calpain inhibitors treatment and combined therapies on Spinal Muscular Atrophy
  • Nuevas terapias para el tratamiento de la Atrofia Muscular Espinal: inhibidores de la calpaina y células madre mesenquimales modificadas
  • Desarrollo de nuevas estrategias terapéuticas para el tratamiento de la atrofia muscular espinal: regulación de la autofagia y las vías de señalización intracelular
  • Estudio degeneración de lasl motoneuronas en un model celular de atrofia muscular espinal
  • ESTUDIO SOBRE LA INTEGRACION DE LAS VIAS DE SEÑALIZACION INTRACELULAR RESPONSABLES DE LA SUPERVIVENCIA DE LAS MOTONEURONAS ESPINALES Y SU IMPLICACION EN LAS ENFERMEDADES NEURODEGENERATIVAS
  • Papel funcional del estrés oxidativo y nitrosativo en grandes sistemas biológicos.