Directori de persones
Daniel Sanchis Morales

Daniel Sanchis Morales

Grau: Doctor/a

973 702215/2949
daniel.sanchis(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/C-8077-2009

Publicacions

  • Gao, SY; Yang, QC; Peng, Y; Kong, WX; Liu, ZK; Li, Z; Chen, JW; Bao, MM; Li, X; Zhang, YB; Bian, XH; Jin, L; Zhang, HW; Zhang, YX; Sanchis, D; Yan, FR; Ye, JM

    SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart.

    CELL BIOLOGY AND TOXICOLOGY 39 1489-1507. .

    [doi:10.1007/s10565-022-09735-z]

  • Beà A; García Valero J; Irazoki A; Lana C; López-Lluch G; Portero-Otín M; Pérez-Galán P; Inserte J; Ruiz-Meana M; Zorzano A; Llovera M; Sanchis D

    Cardiac fibroblasts display endurance to ischemia, high ROS control and elevated respiration regulated by the JAK2/STAT pathway.

    FEBS Journal 289 2540-2561. .

    [doi:10.1111/febs.16283]

  • Barés G; Beà A; Hernández L; Navaridas R; Felip I; Megino C; Blasco N; Nadeu F; Campo E; Llovera M; Dolcet X; Sanchis D

    ENDOG Impacts on Tumor Cell Proliferation and Tumor Prognosis in the Context of PI3K/PTEN Pathway Status.

    Cancers 13 -. .

    [doi:10.3390/cancers13153803]

  • Witte F; Ruiz-Orera J; Mattioli CC; Blachut S; Adami E; Schulz JF; Schneider-Lunitz V; Hummel O; Patone G; Mücke MB; Šilhavý J; Heinig M; Bottolo L; Sanchis D; Vingron M; Chekulaeva M; Pravenec M; Hubner N; van Heesch S

    A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.

    GENOME BIOLOGY 22 191-191. .

    [doi:10.1186/s13059-021-02397-w]

  • Blasco N; Beà A; Barés G; Girón C; Navaridas R; Irazoki A; López-Lluch G; Zorzano A; Dolcet X; Llovera M; Sanchis D

    Involvement of the mitochondrial nuclease EndoG in the regulation of cell proliferation through the control of reactive oxygen species

    Redox Biology 37 101736-101736. .

    [doi:10.1016/j.redox.2020.101736]

  • Chen, M; Ji, CY; Yang, QC; Gao, SY; Peng, Y; Li, Z; Gao, XY; Li, YT; Jiang, N; Zhang, YB; Bian, XH; Chen, CP; Zhang, KD; Sanchis, D; Yan, FR; Ye, JM

    AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.

    CLINICAL SCIENCE 134 2381-2398. .

    [doi:10.1042/CS20191320]

  • Saez, ME; Gonzalez-Perez, A; Hernandez-Olasagarre, B; Bea, A; Moreno-Grau, S; de Rojas, I; Monte-Rubio, G; Orellana, A; Valero, S; Comella, JX; Sanchis, D; Ruiz, A

    Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer's disease

    SCIENTIFIC REPORTS 9 16665-16665. .

    [doi:10.1038/s41598-019-52724-2]

  • Chen, DD; Li, Z; Bao, PQ; Chen, M; Zhang, M; Yan, FR; Xu, YT; Ji, CY; Hu, XY; Sanchis, D; Zhang, YB; Ye, JM

    Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1865 1253-1264. .

    [doi:10.1016/j.bbadis.2019.01.020]

  • Blasco, N; Camara, Y; Núñez E.; Bea, A; Bares, G; Forne, C; Ruiz-Meana, M; Giron, C; Barba, I; Garcia-Arumi, E; Garcia-Dorado, D; Vazquez, J; Marti, R; Llovera, M; Sanchis, D

    Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin

    Redox Biology 16 146-156. .

    [doi:10.1016/j.redox.2018.02.021]

  • Yang, S; Chen, DD; Chen, F; Zhao, XM; Zhang, YB; Li, Z; Jin, L; Xu, YT; Sanchis, D; Ye, JM

    Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II/high-salt-diet-induced hypertension

    JOURNAL OF HYPERTENSION 36 834-846. .

    [doi:10.1097/HJH.0000000000001613]

  • Torres, P; Ramirez-Nunez, O; Romero-Guevara, R; Bares, G; Granado-Serrano, AB; Ayala, V; Boada, J; Fontdevila, L; Povedano, M; Sanchis, D; Pamplona, R; Ferrer, I; Portero-Otin, M

    Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue

    Autophagy 14 1398-1403. .

    [doi:10.1080/15548627.2018.1474311]

  • Chen, F; Chen, DD; Zhao, XM; Yang, S; Li, Z; Sanchis, D; Jin, L; Qiang, XZ; Wang, KY; Xu, YT; Zhang, YB; Ye, JM

    Interleukin-6 deficiency facilitates myocardial dysfunction during high fat diet-induced obesity by promoting lipotoxicity and inflammation

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1863 3128-3141. .

    [doi:10.1016/j.bbadis.2017.08.022]

Projectes

  • Señalización celular en el corazón y metabolismo: supervivencia y nuevas funciones de los fibroblastos cardíacos y el papel de ENDOG en la homeostasis metabólica.
  • INVESTIGO 2022: Senyalització cel·lular i apoptosi
  • Mechanisms involved in the role of EndoG in the development and metabolism of the heart. Relationship of ENDOG and other apoptotic genes with cardiac pathophysiology
  • New molecular functions of apoptotic genes in cardiac development and stress
  • Vías de señalización para desarrollo y muerte celular en el miocardio: estudio integrativo para su comprensión e identificación de dianas terapéuticas.
  • PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES
  • Identificación de nuevas funciones y miembros de la via de señalización apoptotica en el desarrollo y patologia del corazon
  • Caracterización de la función the las Deacetilasas de Histonas en la coordinación entre apoptosis y diferenciación en el corazón
  • RELEVANCIA DE LA MUERTE CELULAR POR APOPTOSIS EN PATOLOGIAS CARDIOVASCULARES QUE CURSAN CON LESION CELULAR