Area: Cancer
Area coordinator: Dr. Eloi Garí Marsol
The cancer area includes research staff trained in different specialties of Medicine and Biology. The common goal is oncology research integrating basic (model organisms), translational, and clinical research (trials).
< Research
Calcium cellular signalling
During tumor progression, cancer cells adapt to changes in the microenvironment (lack of nutrients and /or oxygen) through the activation of stress pathways and autophagy...
Cell cycle
The Cell Cycle group studies the molecular mechanisms that regulate the division of eukaryotic cells, in particular: (A) the mechanisms dependent on SUMO and SMC complexes that ensure genome stability during the cycle and in response to DNA damage...
Developmental and oncogenic signaling
The group considers a genetic approach to the mechanisms that regulate the activated cell signaling pathways by proto-oncogen Ret, and its regulation by the putative tumor suppressor Sprouty...
Drosophila Models of Disease
Our group has developed a metastatic model of colorectal cancer in Drosophila, with the aim to unravel the basic mechanisms that allow the spread of tumor cells outside the primary tumor and the colonization of distant sites...
Molecular Oncology
The main interest of our laboratory is the study of molecular events underlying the oncogenic process, especially in colorectal, gastric and head-and-neck cancer...
Oncological pathology
The group studies the molecular alterations of endometrial and skin cancers, in correlation with clinical and pathological characteristics, using descriptive molecular pathology tools (immunohistochemistry, in situ hybridization, sequencing, epigenetics, gene gain and loss), as well as in vitro functional analysis in cell cultures (2D and 3D), and experimental animals...
Research group of Cancer Biomarkers (GReBiC)
Our research group is translational, multidisciplinary and young. It is composed of medical doctors specialized in Medical Oncology, Internal Medicine, Radiotherapy Oncology and Clinical Analysis; and basic researchers trained in Biosciences (Biology, Biochemistry, Biomedicine and Biotechnology) with a high degree of cohesion...
