Directory
Joaquim Ros Salvador

Joaquim Ros Salvador

Degree: PhD

973 702 275
joaquim.ros(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7507-2010

Groups

Publications

  • Echave, P; Esparza-Ceron, MA; Cabiscol, E; Tamarit, J; Ros, J; Membrillo-Hernandez, J; Lin, ECC

    DnaK dependence of mutant ethanol oxidoreductases evolved for aerobic function and protective role of the chaperone against protein oxidative damage in Escherichia coli.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 4626-4631. .

    [doi:10.1073/pnas.072504199]

  • Rodriguez-Manzaneque, MT; Tamarit, J; Belli, G; Ros, J; Herrero, E

    Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes.

    MOLECULAR BIOLOGY OF THE CELL 13 1109-1121. .

    [doi:10.1091/mbc.01-10-0517]

  • Herrero E; Ros J

    Glutaredoxins and oxidative stress defense in yeast.

    METHOD ENZYMOL 348 136-146. .

  • Belli, G; Rodriguez-Manzaneque, MT; Torres, J; Tamarit, J; Ros, J; Herrero, E

    Characterisation of essential residues for the activity of the Saccharomyces cerevisiae Grx5 monothiol glutaredoxin.

    YEAST 18 171-171. .

  • Rodriguez-Manzaneque, MT; Tamarit, J; Belli, G; de la Torre, MA; Ros, J; Herrero, E

    The mitochondrial Grx5 glutaredoxin is involved in Fe/S cluster assembly and iron homeostasis in Saccharomyces cerevisiae.

    YEAST 18 172-172. .

  • Membrillo-Hernandez, J; Echave, P; Cabiscol, E; Tamarit, J; Ros, J; Lin, ECC

    Evolution of the adhE gene product of Escherichia coli from a functional reductase to a dehydrogenase. Genetic and biochemical studies of the mutant proteins.

    Journal Of Biological Chemistry 275 33869-33875. .

    [doi:10.1074/jbc.M005464200]

  • Cabiscol, E; Piulats, E; Echave, P; Herrero, E; Ros, J

    Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae.

    Journal Of Biological Chemistry 275 27393-27398. .

    [doi:10.1074/jbc.M003140200]

  • Rodriguez-Manzaneque, MT; Ros, J; Cabiscol, E; SORRIBAS, A; Herrero, E

    Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae.

    MOLECULAR AND CELLULAR BIOLOGY 19 8180-8190. .

  • Obradors, N; Cabiscol, E; Aguilar, J; Ros, J

    Site-directed mutagenesis studies of the metal-binding center of the iron-dependent propanediol oxidoreductase from Escherichia coli.

    European Journal Of Biochemistry 258 207-213. .

    [doi:10.1046/j.1432-1327.1998.2580207.x]

  • Lu, Z; Cabiscol, E; Obradors, N; Tamarit, J; Ros, J; Aguilar, J; Lin, ECC

    Evolution of an Escherichia coli protein with increased resistance to oxidative stress.

    Journal Of Biological Chemistry 273 8308-8316. .

    [doi:10.1074/jbc.273.14.8308]

  • Tamarit, J; Cabiscol, E; Ros, J

    Identification of the major oxidatively damaged proteins in Escherichia coli cells exposed to oxidative stress.

    Journal Of Biological Chemistry 273 3027-3032. .

    [doi:10.1074/jbc.273.5.3027]

  • Tamarit, J; Cabiscol, E; Aguilar, J; Ros, J

    Differential inactivation of alcohol dehydrogenase isoenzymes in Zymomonas mobilis by oxygen.

    Journal Of Bacteriology 179 1102-1104. .

Projects

  • Pre-clinical assessment of protein replacement therapy in the central nervous system of Friedreich’s ataxia mouse models
  • Uncovering the function of a conserved site in eukaryotic frataxins.
  • Desarrollo de la leriglitazona para el Síndrome de Rett y trastornos relacionados
  • Mecanismos de disfuncion mitocondrial y nuevas estrategias terapéuticas en modelos celulares y animales de Ataxia de Friedreich
  • Nuevo fármaco dirigido a la Ataxia de Friedreich
  • MithrAtaxia: Validació en laboratori dels efects protectors de mithramycin A por un us terapeutic en Ataxia de Friedreich
  • Targeting mitochondria in Friedreich Ataxia: molecular mechanisms and therapeutic approaches
  • Búsqueda de nuevas indicaciones terapéuticas en el ámbito de enfermedades neurodegenerativas y mitocondriales para el compuesto PPAR gamma agonista MIN-102
  • Effect of vitamin D in frataxin-deficient DRG neurons from rat and iPS cells obtained from FA patients
  • MODELOS CELULARES DE ATAXIA DE FRIEDREICH: BASES MOLECULARES DE LA PATOLOGIA E IDENTIFICACION DE BIOMARCADORES Y COMPUESTOS CON POTENCIAL TERAPEUTICO
  • Modelos celulares de ataxia de Friedreich: bases moleculares de la patología e identificación de biomarcadores y compuestos con potencial terapéutico
  • PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES