Area: Cancer

Area coordinator: Dr. Eloi Garí Marsol

The cancer area includes research staff trained in different specialties of Medicine and Biology. The common goal is oncology research integrating basic (model organisms), translational, and clinical research (trials).

< Research

Calcium cellular signalling

Group leaders
  • Carles Cantí Nicolás
  • Judit Herreros Danés

During tumor progression, cancer cells adapt to changes in their microenvironment (devoid of nutrients and/or oxygen) by activating stress pathways and autophagy...

Cell cycle

Group leaders
  • Eloi Garí Marsol
  • Jordi Torres Rosell

The Cell Cycle group studies the molecular mechanisms that regulate the division of eukaryotic cells, in particular: (A) the mechanisms dependent on SUMO and SMC complexes that ensure genome stability during the cycle and in response to DNA damage...

Developmental and oncogenic signaling

Group leader
  • Mario Encinas Martin

The group considers a genetic approach to the mechanisms that regulate the activated cell signaling pathways by proto-oncogen Ret, and its regulation by the putative tumor suppressor Sprouty...

Drosophila Models of Disease

Group leader
  • Andreu Casali Taberner

Our group has developed a metastatic model of colorectal cancer in Drosophila, with the aim to unravel the basic mechanisms that allow the spread of tumor cells outside the primary tumor and the colonization of distant sites...

Molecular Oncology

Group leader
  • Diego Arango Del Corro

The main interest of our laboratory is the study of molecular events underlying the oncogenic process, especially in colorectal, gastric and head-and-neck cancer...

Oncological pathology

Group leader
  • Xavier Matias-Guiu Guia

The group studies the molecular alterations of endometrial and skin cancers, in correlation with clinical and pathological characteristics, using descriptive molecular pathology tools (immunohistochemistry, in situ hybridization, sequencing, epigenetics, gene gain and loss), as well as in vitro functional analysis in cell cultures (2D and 3D), and experimental animals...

Research group of Cancer Biomarkers (GReBiC)

Group leaders
  • Jose Manuel Porcel Pérez
  • Antonia Salud Salvia
  • Maria Alba Sorolla Bardaji

Our group work focuses on three main lines of research lines related to cancer: Digestive tumors: colorectal cancer and gastric cancer Breast cancer Malignant pleural effusion The three lines tackle diseases of high prevalence in our society which are associated with a high mortality rate...