Research > Cellular and molecular models of human pathologies

Cell signalling and apoptosis group

Number of publications
39
Publications search
  • Blasco N; Beà A; Barés G; Girón C; Navaridas R; Irazoki A; López-Lluch G; Zorzano A; Dolcet X; Llovera M; Sanchis D

    Involvement of the mitochondrial nuclease EndoG in the regulation of cell proliferation through the control of reactive oxygen species

    Redox Biology 37 101736-101736. .

    [doi:10.1016/j.redox.2020.101736]

  • David, Monica D.; Yeramian, Andree; Dunach, Mireja; Llovera, Marta; Canti, Carles; Garcia de Herreros, Antonio; Comella, Joan X.; Herreros, Judit

    Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential beta-catenin phosphorylation.

    JOURNAL OF CELL SCIENCE 121 2718-2730. .

    [doi:10.1242/jcs.029660]

  • McDermott-Roe, Chris; Ye, Junmei; Ahmed, Rizwan; Sun, Xi-Ming; Serafin, Anna; Ware, James; Bottolo, Leonardo; Muckett, Phil; Canas, Xavier; Zhang, Jisheng; Rowe, Glenn C.; Buchan, Rachel; Lu, Han; Braithwaite, Adam; Mancini, Massimiliano; Hauton, David; Marti, Ramon; Garcia-Arumi, Elena; Hubner, Norbert; Jacob, Howard; Serikawa, Tadao; Zidek, Vaclav; Papousek, Frantisek; Kolar, Frantisek; Cardona, Maria; Ruiz-Meana, Marisol; Garcia-Dorado, David; Comella, Joan X.; Felkin, Leanne E.; Barton, Paul J. R.; Arany, Zoltan; Pravenec, Michal; Petretto, Enrico; Sanchis, Daniel; Cook, Stuart A.

    Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

    Nature 478 114-118. .

    [doi:10.1038/nature10490]

  • Georgieva, Maya V.; de Pablo, Yolanda; Sanchis, Daniel; Comella, Joan X.; Llovera, Marta

    Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling.

    JOURNAL OF NEUROCHEMISTRY 117 479-493. .

    [doi:10.1111/j.1471-4159.2011.07218.x]

  • Zhang, Jisheng; Ye, Junmei; Altafaj, Albert; Cardona, Maria; Bahi, Nuria; Llovera, Marta; Canas, Xavier; Cook, Stuart A.; Comella, Joan X.; Sanchis, Daniel

    EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes.

    PLOS ONE 6 e17998-. .

    [doi:10.1371/journal.pone.0017998]

  • Moubarak, Rana S.; Sole, Carme; Pascual, Marta; Gutierrez, Humberto; Llovera, Marta; Jose Perez-Garcia, M.; Gozzelino, Raffaella; Segura, Miguel F.; Iglesias-Guimarais, Victoria; Reix, Stephanie; Soler, Rosa M.; Davies, Alun M.; Soriano, Eduardo; Yuste, Victor J.; Comella, Joan X.

    The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

    JOURNAL OF NEUROSCIENCE 30 6094-6105. .

    [doi:10.1523/JNEUROSCI.0537-10.2010]

  • Zhang, J.; Bahi, N.; Llovera, M.; Comella, J. X.; Sanchis, D.

    Polypyrimidine tract binding proteins (PTB) regulate the expression of apoptotic genes and susceptibility to caspase-dependent apoptosis in differentiating cardiomyocytes.

    CELL DEATH AND DIFFERENTIATION 16 1460-1468. .

    [doi:10.1038/cdd.2009.87]

  • Marler, Katharine J. M.; Becker-Barroso, Elena; Martinez, Albert; Llovera, Marta; Wentzel, Corinna; Poopalasundaram, Subathra; Hindges, Robert; Soriano, Eduardo; Comella, Joan; Drescher, Uwe

    A TrkB/Ephrina Interaction Controls Retinal axon Branching and Synaptogenesis

    JOURNAL OF NEUROSCIENCE 28 12700-12712. .

    [doi:10.1523/JNEUROSCI.1915-08.2008]

  • Gozzelino, Raffaella; Sole, Carme; Llecha, Nuria; Segura, Miguel F.; Moubarak, Rana S.; Iglesias-Guimarais, Victoria; Perez-Garcia, M. Jose; Reix, Stephanie; Zhang, Jisheng; Badiola, Nahuai; Sanchis, Daniel; Rodriguez-Alvarez, Jose; Trullas, Ramon; Yuste, Victor J.; Comella, Joan X.

    BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.

    Cell Research 18 1020-1036. .

    [doi:10.1038/cr.2008.76]

  • Perez-Garcia, M. Jose; Gou-Fabregas, Myriam; de Pablo, Yolanda; Llovera, Marta; Comella, Joan X.; Soler, Rosa M.

    Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV.

    Journal Of Biological Chemistry 283 4133-4144. .

    [doi:10.1074/jbc.M705477200]

  • Ye J; Llorian M; Cardona M; Rongvaux A; Moubarak RS; Comella JX; Bassel-Duby R; Flavell RA; Olson EN; Smith CW; Sanchis D

    A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

    JOURNAL OF CELL SCIENCE 126 1682-1691. .

    [doi:10.1242/jcs.121384]

  • Sanchis, Daniel; Llovera, Marta; Ballester, Mane; Comella, Joan X.

    An alternative view of apoptosis in heart development and disease.

    CARDIOVASCULAR RESEARCH 77 448-451. .

    [doi:10.1093/cvr/cvm074]