Cell polarity in retinal pathologies
- External Seminar
- Thursday, June 17, 2021
Dr. Mª Concepción Lillo Delgado
Cell Biology and Pathology Dept.
Instituto de Neurociencias de Castilla y León (INCyL)
University of Salamanca
In our laboratory we are interested in understanding the cellular and molecular mechanisms involved in some degenerative disorders of the visual and central nervous system. We investigate the role of a group of cell polarity proteins and their possible involvement in the development of these degenerative diseases. Understanding the role of these proteins in the development of degenerative pathologies of the nervous system will be very useful for the development of more precise tools to design appropriate therapeutic strategies. In this talk we will discuss how the defect of one of these polarity proteins in the retinal pigment epithelium, through protein silencing, triggers functional alterations in this cell type, both in vitro and in vivo.