Cell Signalling in Yeast

Our current research areas have both a basic and applied orientation:

Basic orientation:

1. Responses to stress mediated by signal transduction pathways (TOR, Ras / PKA, AMPK/Snf1, Pkc1-MAPK, GCN2, PDK1/YPK1 ...).
2. Study of the mechanisms of iron homeostasis, its relationship with the recycling of nutrients through autophagy and its impact on aging and mortality in Saccharomyces. cerevisiae, with a transnational objective towards studies related to iron deficiency anemia and breast cancer.
3. Humanization of yeast with human ferritins in order to delve into the mechanisms of iron homeostasis and cell survival.

Applied orientation:

1. Design of strategies to increase endogenous iron levels for use as a nutritional supplement.
2. Design strategies for directed evolution to obtain improved strains for use in food production.