Directory
Sara Hernández Estañol

Sara Hernández Estañol

Degree: PhD

973 70 2416
sara.hernandez(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/N-4017-2014

Groups

Publications

  • Hernández, S; Salvany, S; CASANOVAS, A; PIEDRAFITA, L; Soto-Bernardini, MC; Tarabal, O; Blasco, A; Gras, S; Gatius, A; Schwab, MH; Calderó, J; ESQUERDA, JE

    Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1G93A Mice

    NEUROTHERAPEUTICS 20 1820-1834. .

    [doi:10.1007/s13311-023-01424-x]

  • Salvany, S; CASANOVAS, A; PIEDRAFITA, L; Gras, S; Blasco, A; Gatius, A; Tarabal, O; Hernandez, S; CALDERO, J; ESQUERDA, JE

    Necroptosis and microglial phagocytosis of extracellular vesicles as an early mechanisms involved in the disruption of afferent synaptic terminals on spinal cord motor neurons after acute peripheral nerve injury

    Glia 69 317-318. .

  • Salvany S; Casanovas A; Piedrafita L; Tarabal O; Hernández S; Calderó J; Esquerda JE

    Microglial recruitment and mechanisms involved in the disruption of afferent synaptic terminals on spinal cord motor neurons after acute peripheral nerve injury.

    Glia 69 1216-1240. .

    [doi:10.1002/glia.23959]

  • Gatius, A; Tarabal, O; Cayuela, P; Casanovas, A; Piedrafita, L; Salvany, S; Hernandez, S; Soler, RM; Esquerda, JE; Caldero, J

    The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons

    FRONTIERS IN CELLULAR NEUROSCIENCE 13 582-582. .

    [doi:10.3389/fncel.2019.00582]

  • Salvany, S; Casanovas, A; Tarabal, O; Piedrafita, L; Hernandez, S; Santafe, M; Soto-Bernardini, MC; Caldero, J; Schwab, MH; Esquerda, JE

    Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair

    FASEB JOURNAL 33 7833-7851. .

    [doi:10.1096/fj.201802329R]

  • Rando, A; de la Torre, M; Martinez-Muriana, A; Zaragoza, P; Musaro, A; Hernandez, S; Navarro, X; Toivonen, JM; Osta, R

    Chemotherapeutic agent 5-fluorouracil increases survival of SOD1 mouse model of ALS

    PLOS ONE 14 -. .

    [doi:10.1371/journal.pone.0210752]

  • Casanovas, A; Salvany, S; Lahoz, V; Tarabal, O; Piedrafita, L; Sabater, R; Hernandez, S; Caldero, J; Esquerda, JE

    Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury

    SCIENTIFIC REPORTS 7 40155-40155. .

    [doi:10.1038/srep40155]

  • Staats KA; Hernandez S; Schönefeldt S; Bento-Abreu A; Dooley J; Van Damme P; Liston A; Robberecht W; Van Den Bosch L

    Rapamycin increases survival in ALS mice lacking mature lymphocytes

    MOLECULAR NEURODEGENERATION 8 31-31. .

    [doi:10.1186/1750-1326-8-31]

  • Sábado J; Casanovas A; HERNÁNDEZ ESTAÑOL, SARA; Piedrafita L; Hereu M; Esquerda JE

    Immunodetection of Disease-Associated Conformers of Mutant Cu/Zn Superoxide Dismutase 1 Selectively Expressed in Degenerating Neurons in Amyotrophic Lateral Sclerosis

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 72 646-661. .

    [doi:10.1097/NEN.0b013e318297fd10]

  • Texido, Laura; Hernandez, Sara; Martin-Satue, Mireia; Povedano, Monica; Casanovas, Anna; Esquerda, Josep; Marsal, Jordi; Solsona, Caries

    Sera from amyotrophic lateral sclerosis patients induce the non-canonical activation of NMDA receptors "in vitro".

    NEUROCHEMISTRY INTERNATIONAL 59 954-964. .

    [doi:10.1016/j.neuint.2011.07.006]

  • Hernandez, Sara; Texido, Laura; Caldero, Jordi; Ciutat, Dolors; Piedrafita, Lidia; Casanovas, Anna; Blasi, Joan; Solsona, Carles; Povedano, Monica; Rojas, Ricardo; Illa, Isabel; Caress, James; Prevette, David; Oppenheim, Ronald W.; Milligan, Carol; Esquerda, Josep E.

    Increased intramuscular nerve branching and inhibition of programmed cell death of chick embryo motoneurons by immunoglobulins from patients with motoneuron disease.

    Journal Of Neuroimmunology 229 157-168. .

    [doi:10.1016/j.jneuroim.2010.07.028]

  • Hernández S; Casanovas A; Piedrafita L; Tarabal O; Esquerda JE

    Neurotoxic species of misfolded SOD1G93A recognized by antibodies against the P2X4 subunit of the ATP receptor accumulate in damaged neurons of transgenic animal models of amyotrophic lateral sclerosis.

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 69 176-187. .

    [doi:10.1097/NEN.0b013e3181cd3e33]

Projects

  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
  • Caracterización fenotípica y estrategias terapéuticas en modelos murinos de atrofia muscular espinal (AME)
  • Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental