Directory
Jordi Calderó Pardo

Jordi Calderó Pardo

Degree: PhD

973 702 440
jordi.caldero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7373-2010

Groups

Publications

  • Brunet, Nuria; Tarabal, Olga; Esquerda, Josep E.; Caldero, Jordi

    Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.

    Journal Of Comparative Neurology 516 277-290. .

    [doi:10.1002/cne.22118]

  • Caldero, Jordi; Brunet, Nuria; Ciutat, Dolors; Hereu, Marta; Esquerda, Josep E.

    Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death.

    Journal Of Neuroscience Research 87 2447-2466. .

    [doi:10.1002/jnr.22084]

  • Oppenheim, Ronald W.; Caldero, Jordi; Cuitat, Doloros; Esquerda, Josep; McArdle, Joseph J.; Olivera, Baldornero M.; Prevette, David; Teichert, Russell W.

    The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor.

    Developmental Neurobiology 68 972-980. .

    [doi:10.1002/dneu.20636]

  • Caldero, Jordi; Tarabal, Olga; Casanovas, Anna; Ciutat, Dolors; Casas, Celia; Llado, Jeronia; Esquerda, Josep E.

    Excitotoxic motoneuron disease in chick embryo evolves with autophagic neurodegeneration and deregulation of neuromuscular innervation.

    Journal Of Neuroscience Research 85 2726-2740. .

    [doi:10.1002/jnr.21174]

  • Brunet, Nuria; Tarabal, Olga; Portero-Otin, Manel; Oppenheim, Ronald W.; Esquerda, Josep E.; Caldero, Jordi

    Survival and death of mature avian motoneurons in organotypic slice culture: trophic requirements for survival and different types of degeneration.

    Journal Of Comparative Neurology 501 669-690. .

    [doi:10.1002/cne.21157]

  • Tarabal, O; CALDERO, J; Casas, C; Oppenheim, RW; ESQUERDA, JE

    Protein retention in the endoplasmic reticulum, blockade of programmed cell death and autophagy selectively occur in spinal cord motoneurons after glutamate receptor-mediated injury.

    MOLECULAR AND CELLULAR NEUROSCIENCE 29 283-298. .

    [doi:10.1016/j.mcn.2005.03.003]

  • Oppenheim, RW; CALDERO, J; Cuitat, D; Esquerda, J; Ayala, V; Prevette, D; Wang, SW

    Rescue of developing spinal motoneurons from programmed cell death by the GABA(A) agonist muscimol acts by blockade of neuromuscular activity and increased intramuscular nerve branching.

    MOLECULAR AND CELLULAR NEUROSCIENCE 22 331-343. .

    [doi:10.1016/S1044-7431(02)00020-9]

  • Winseck, AK; CALDERO, J; CIUTAT, D; Prevette, D; Scott, SA; Wang, GY; ESQUERDA, JE; Oppenheim, RW

    In vivo analysis of Schwann cell programmed cell death in the embryonic chick: regulation by axons and glial growth factor.

    JOURNAL OF NEUROSCIENCE 22 4509-4521. .

    [doi:20026391]

  • Tarabal, O; CALDERO, J; Llado, J; Oppenheim, RW; ESQUERDA, JE

    Long-lasting aberrant tubulovesicular membrane inclusions accumulate in developing motoneurons after a sublethal excitotoxic insult: a possible model for neuronal pathology in neurodegenerative disease.

    JOURNAL OF NEUROSCIENCE 21 8072-8081. .

  • Tarabal, O; LladoJ, OJ; CALDERO, J; Ribera, J; CIUTAT, D; CASANOVAS, A; Ayala, V; Serrando, M; Casas, C; Sarasa, M; ESQUERDA, JE

    Chronic NMDa treatment results in a prevention of acute excitotoxic injury at tm chick embryo motoneurons and induces permanent changes in intracellular membrane compartimentation.

    EUROPEAN JOURNAL OF NEUROSCIENCE 12 38-38. .

  • CALDERO, J; Llado, J; Ribera, J; Tarabal, O; CIUTAT, D; CASANOVAS, A; Ayala, V; Casas, C; Serrando, M; Oppenheim, RW; ESQUERDA, JE

    Chronic administration of n-methyl-d-aspartate (NMDa) prevents excitotoxicity and normal and induced programmed cell death in spinal cord motoneurons.

    EUROPEAN JOURNAL OF NEUROSCIENCE 12 394-394. .

  • CASANOVAS, A; Ribera, J; Hager, G; Kreutzberg, GW; Casas, C; Ayala, V; CALDERO, J; CIUTAT, D; Tarabal, O; Llado, J; Serrando, M; ESQUERDA, JE

    Differential expression of c-jun after axotomy in neonatals suggest different functions in programmed cell death and axonal regeneration.

    EUROPEAN JOURNAL OF NEUROSCIENCE 12 8-8. .

Projects

  • Mecanismos subyacentes a la patología del circuito motor y la miopatía primaria en atrofia muscular espinal: identificación de dianas para terapias combinadas con nusinersen
  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • El sistema NRG1-ErbBs en la arquitectura molecular de las sinapsis aferentes de tipo C y su significado en las enfermedades de la motoneurona
  • Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
  • Caracterización fenotípica y estrategias terapéuticas en modelos murinos de atrofia muscular espinal (AME)
  • Mecanismos de neurodegeneración en modelos animales de atrofia muscular espinal y ensayos de neuroprotección con litio
  • Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental
  • Mecanismos de degeneración excitotóxica en las motoneuronas espinales y efecto neuroprotector del litio: relevancia en el contexto de la esclerosis lateral amiotrófica