 
            Jordi Calderó Pardo
Degree: PhD
                973 702 440                
                jordi.caldero(ELIMINAR)@udl.cat
            
ResearcherID: http://www.researcherid.com/rid/A-7373-2010
Publications
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                        Caldero, J.; Brunet, N.; Tarabal, O.; Piedrafita, L.; Hereu, M.; Ayala, V.; Esquerda, J. E. Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord.NEUROSCIENCE 165 1353-1369. . 
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                        Brunet, Nuria; Tarabal, Olga; Esquerda, Josep E.; Caldero, Jordi Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.Journal Of Comparative Neurology 516 277-290. . 
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                        Caldero, Jordi; Brunet, Nuria; Ciutat, Dolors; Hereu, Marta; Esquerda, Josep E. Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death.Journal Of Neuroscience Research 87 2447-2466. . 
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                        Oppenheim, Ronald W.; Caldero, Jordi; Cuitat, Doloros; Esquerda, Josep; McArdle, Joseph J.; Olivera, Baldornero M.; Prevette, David; Teichert, Russell W. The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor.Developmental Neurobiology 68 972-980. . 
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                        Caldero, Jordi; Tarabal, Olga; Casanovas, Anna; Ciutat, Dolors; Casas, Celia; Llado, Jeronia; Esquerda, Josep E. Excitotoxic motoneuron disease in chick embryo evolves with autophagic neurodegeneration and deregulation of neuromuscular innervation.Journal Of Neuroscience Research 85 2726-2740. . 
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                        Brunet, Nuria; Tarabal, Olga; Portero-Otin, Manel; Oppenheim, Ronald W.; Esquerda, Josep E.; Caldero, Jordi Survival and death of mature avian motoneurons in organotypic slice culture: trophic requirements for survival and different types of degeneration.Journal Of Comparative Neurology 501 669-690. . 
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                        Tarabal, O; CALDERO, J; Casas, C; Oppenheim, RW; ESQUERDA, JE Protein retention in the endoplasmic reticulum, blockade of programmed cell death and autophagy selectively occur in spinal cord motoneurons after glutamate receptor-mediated injury.MOLECULAR AND CELLULAR NEUROSCIENCE 29 283-298. . 
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                        Oppenheim, RW; CALDERO, J; Cuitat, D; Esquerda, J; Ayala, V; Prevette, D; Wang, SW Rescue of developing spinal motoneurons from programmed cell death by the GABA(A) agonist muscimol acts by blockade of neuromuscular activity and increased intramuscular nerve branching.MOLECULAR AND CELLULAR NEUROSCIENCE 22 331-343. . 
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                        Winseck, AK; CALDERO, J; CIUTAT, D; Prevette, D; Scott, SA; Wang, GY; ESQUERDA, JE; Oppenheim, RW In vivo analysis of Schwann cell programmed cell death in the embryonic chick: regulation by axons and glial growth factor.JOURNAL OF NEUROSCIENCE 22 4509-4521. . 
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                        Tarabal, O; CALDERO, J; Llado, J; Oppenheim, RW; ESQUERDA, JE Long-lasting aberrant tubulovesicular membrane inclusions accumulate in developing motoneurons after a sublethal excitotoxic insult: a possible model for neuronal pathology in neurodegenerative disease.JOURNAL OF NEUROSCIENCE 21 8072-8081. . 
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                        Tarabal, O; LladoJ, OJ; CALDERO, J; Ribera, J; CIUTAT, D; CASANOVAS, A; Ayala, V; Serrando, M; Casas, C; Sarasa, M; ESQUERDA, JE Chronic NMDa treatment results in a prevention of acute excitotoxic injury at tm chick embryo motoneurons and induces permanent changes in intracellular membrane compartimentation.EUROPEAN JOURNAL OF NEUROSCIENCE 12 38-38. . 
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                        CALDERO, J; Llado, J; Ribera, J; Tarabal, O; CIUTAT, D; CASANOVAS, A; Ayala, V; Casas, C; Serrando, M; Oppenheim, RW; ESQUERDA, JE Chronic administration of n-methyl-d-aspartate (NMDa) prevents excitotoxicity and normal and induced programmed cell death in spinal cord motoneurons.EUROPEAN JOURNAL OF NEUROSCIENCE 12 394-394. . 
Projects
- Mecanismos subyacentes a la patología del circuito motor y la miopatía primaria en atrofia muscular espinal: identificación de dianas para terapias combinadas con nusinersen
- Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
- El sistema NRG1-ErbBs en la arquitectura molecular de las sinapsis aferentes de tipo C y su significado en las enfermedades de la motoneurona
- Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
- Caracterización fenotípica y estrategias terapéuticas en modelos murinos de atrofia muscular espinal (AME)
- Mecanismos de neurodegeneración en modelos animales de atrofia muscular espinal y ensayos de neuroprotección con litio
- Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental
- Mecanismos de degeneración excitotóxica en las motoneuronas espinales y efecto neuroprotector del litio: relevancia en el contexto de la esclerosis lateral amiotrófica