Directory
Josep Enric Esquerda Colell

Josep Enric Esquerda Colell

Degree: Doctor

973 702 427
josep.esquerda(ELIMINAR)@mex.udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7377-2010

Publications

  • Salvany S; Casanovas A; Tarabal O; Piedrafita L; Hernández S; Santafé M; Soto-Bernardini MC; Calderó J; Schwab MH; Esquerda JE

    Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair.

    FASEB JOURNAL 33 201802329-201802329. .

    [doi:10.1096/fj.201802329R]

  • Cervero, Claudia; Blasco, Alba; Tarabal, Olga; Casanovas, Anna; Piedrafita, Lidia; Navarro, Xavier; Esquerda, Josep E.; Caldero, Jordi

    Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn(2B/-) Mouse Model of Spinal Muscular Atrophy

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 77 577-597. .

    [doi:10.1093/jnen/nly033]

  • Casanovas A; Salvany S; Lahoz V; Tarabal O; Piedrafita L; Sabater R; Hernández S; Calderó J; Esquerda JE

    Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury

    SCIENTIFIC REPORTS 7 40155-40155. .

    [doi:10.1038/srep40155]

  • Cerveró C; Montull N; Tarabal O; Piedrafita L; Esquerda JE; Calderó J

    Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy

    NEUROTHERAPEUTICS 13 198-216. .

    [doi:10.1007/s13311-015-0399-x]

  • Sábado, J.; Casanovas, A.; Rodrigo, H.; Arqué, G.; Esquerda, J.E.

    ADVERSE EFFECTS OF A SOD1-PEPTIDE IMMUNOTHERAPY ON SOD1(G93A) MOUSE SLOW MODEL OF AMYOTROPHIC LATERAL SCLEROSIS

    NEUROSCIENCE 310 38-50. .

    [doi:10.1016/j.neuroscience.2015.09.027]

  • Gallart-Palau X; Tarabal O; Casanovas A; Sábado J; Correa FJ; Hereu M; Piedrafita L; Calderó J; Esquerda JE

    Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to alpha-motoneurons and altered during motoneuron diseases

    FASEB JOURNAL 28 3618-3632. .

    [doi:10.1096/fj.13-248583]

  • Tarabal O; Caraballo-Miralles V; Cardona-Rossinyol A; Correa FJ; Olmos G; Lladó J; Esquerda JE; Calderó J

    Mechanisms Involved in Spinal Cord Central Synapse Loss in a Mouse Model of Spinal Muscular Atrophy

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 73 519-535. .

    [doi:10.1097/NEN.0000000000000074]

  • Sabado, Javier; Casanovas, Anna; Tarabal, Olga; Hereu, Marta; Piedrafita, Ldia; Caldero, Jordi; Esquerda, Josep E.

    Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis

    BioMed Research International 852163-. .

    [doi:10.1155/2014/852163]

  • Dachs E; Piedrafita L; Hereu M; Esquerda JE; Calderó J

    CHRONIC TREATMENT WITH LITHIUM DOES NOT IMPROVE NEUROMUSCULAR PHENOTYPE IN A MOUSE MODEL OF SEVERE SPINAL MUSCULAR ATROPHY

    NEUROSCIENCE 250 417-433. .

    [doi:10.1016/j.neuroscience.2013.07.026]

  • Sábado J; Casanovas A; HERNÁNDEZ ESTAÑOL, SARA; Piedrafita L; Hereu M; Esquerda JE

    Immunodetection of Disease-Associated Conformers of Mutant Cu/Zn Superoxide Dismutase 1 Selectively Expressed in Degenerating Neurons in Amyotrophic Lateral Sclerosis

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 72 646-661. .

    [doi:10.1097/NEN.0b013e318297fd10]

  • Martinez-Hernandez, Rebeca; Bernal, Sara; Also-Rallo, Eva; Alias, Laura; Jesus Barcelo, Ma; Hereu, Marta; Esquerda, Josep E.; Tizzano, Eduardo F.

    Synaptic defects in type I spinal muscular atrophy in human development

    JOURNAL OF PATHOLOGY 229 49-61. .

    [doi:10.1002/path.4080]

  • Texido, Laura; Hernandez, Sara; Martin-Satue, Mireia; Povedano, Monica; Casanovas, Anna; Esquerda, Josep; Marsal, Jordi; Solsona, Caries

    Sera from amyotrophic lateral sclerosis patients induce the non-canonical activation of NMDA receptors "in vitro".

    NEUROCHEMISTRY INTERNATIONAL 59 954-964. .

    [doi:10.1016/j.neuint.2011.07.006]

Projects

  • Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
  • Neurobiologia Cel·lular
  • La esclerosis lateral amiotrófica como enfermedad proteinopática y neuroimflamatoria: estrategias de inmunoterapia (Vacunas y ELA)
  • Excitotoxicidad, plegamiento anómalo de proteinas y mecanismos inmunológicos en la esclerosis lateral amiotrófica
  • Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental