Directorio de personas
Manuel Portero Otin

Manuel Portero Otin

Grado: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Grupos

Publicaciones

  • Portero-Otin, M; Pamplona, R; Ruiz, MC; Cabiscol, E; Prat, J; Bellmunt, MJ

    Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney.

    Diabetes 48 2215-2220. .

    [doi:10.2337/diabetes.48.11.2215]

  • Pamplona, R; Portero-Otin, M; Ruiz, C; Bellmunt, MJ; Requena, JR; Thorpe, SR; Baynes, JW; Romero, M; Lopez-Torres, M; Barja, G

    Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins.

    FREE RADICAL BIOLOGY AND MEDICINE 27 901-910. .

    [doi:10.1016/S0891-5849(99)00135-5]

  • Portero-Otin, M

    Report of a 1998 EaSD-Bayer Travel Fellowship for Yound Scientists - Effect of oxidized LDL and glucose in tyrosine kinase receptors

    Diabetologia 42 37-38. .

  • Pamplona, R; Portero-Otin, M; Riba, D; Ledo, F; Gredilla, R; Herrero, A; Barja, G

    Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse.

    Zeitschrift Fur Gerontologie Und Geriatrie 32 883-883. .

  • Pamplona, R; Portero-Otin, M; Riba, D; Ledo, F; Gredilla, R; Herrero, A; Barja, G

    Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse.

    Aging-Clinical And Experimental Research 11 44-49. .

  • Pamplona, R; Portero-Otin, M; Requena, JR; Thorpe, SR; Herrero, A; Barja, G

    A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat.

    MECHANISMS OF AGEING AND DEVELOPMENT 106 283-296. .

    [doi:10.1016/S0047-6374(98)00121-3]

  • Guerrero, A; Pamplona, R; Portero-Otin, M; Barja, G; Lopez-Torres, M

    Effect of thyroid status on lipid composition and peroxidation in the mouse liver.

    FREE RADICAL BIOLOGY AND MEDICINE 26 73-80. .

    [doi:10.1016/S0891-5849(98)00173-7]

  • Pamplona, R; Portero-Otin, M; Riba, D; Ruiz, C; Prat, J; Bellmunt, MJ; Barja, G

    Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals.

    Journal Of Lipid Research 39 1989-1994. .

  • Pamplona R; Requena JR; Portero-Otín M; Prat J; Thorpe SR; Bellmunt MJ

    Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals--evidence for intracellular lipid glycoxidation.

    European Journal Of Biochemistry 255 685-689. .

  • Pamplona, R; Requena, JR; Portero-Otin, M; Prat, J; Thorpe, SR; Bellmunt, MJ

    Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals - Evidence for intracellular lipid glycoxidation

    European Journal Of Biochemistry 255 685-689. .

    [doi:10.1046/j.1432-1327.1998.2550685.x]

  • Portero-Otin, A; Pamplona, R; Riba, D; Ruiz, C; Lafarga, MA; Bellmunt, MJ; Prat, J

    Evidence against a diabetes induced generalized increase of oxidative damage in liver cytosolic proteins

    Diabetologia 41 1243-1243. .

  • PorteroOtin, M; Pamplona, R; Bellmunt, MJ; Bergua, M; Prat, J

    Glycaemic control and in vivo non-oxidative Maillard reaction: urinary excretion of pyrraline in diabetes patients.

    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 27 767-773. .

    [doi:10.1046/j.1365-2362.1997.1900740.x]

Proyectos

  • SEED-ALS: Synergizing Efforts to Develop and Accelerate Breakthroughs in ALS Research
  • Natural microbicides from rice against current and emerging infectious diseases
  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • Comprehensive Roadmap and Preclinical Evaluation of Antisense Oligonucleotides (ASOs) Regulatory Development and Toxicological Assessment for ALS Treatment
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig