Directorio de personas
Manuel Portero Otin

Manuel Portero Otin

Grado: Doctor

973 702 408
manuel.portero(ELIMINAR)@mex.udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Publicaciones

  • Galea, Elena; Launay, Nathalie; Portero-Otin, Manuel; Ruiz, Montserrat; Pamplona, Reinald; Aubourg, Patrick; Ferrer, Isidre; Pujol, Aurora

    Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1822 1475-1488. .

    [doi:10.1016/j.bbadis.2012.02.005]

  • Morató L; Ruiz M; Boada J; Calingasan NY; Galino J; Guilera C; Jové M; Naudí A; Ferrer I; Pamplona R; Serrano M; Portero-Otín M; Beal MF; Fourcade S; Pujol A

    Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy

    CELL DEATH AND DIFFERENTIATION 22 1742-1753. .

    [doi:10.1038/cdd.2015.20]

  • Betriu À; Farràs C; Abajo, M; Martinez-Alonso, M; Arroyo, D; Barbe, F; Buti, M; Lecube, A; Portero, M; Purroy, F; Torres, G; Valdivielso, JM; Fernandez, E

    Randomised intervention study to assess the prevalence of subclinical vascular disease and hidden kidney disease and its impact on morbidity and mortality: The ILERVAS project

    Nefrologia 36 389-396. .

    [doi:10.1016/j.nefro.2016.02.008]

  • Dominguez, M; de Oliveira, E; Odena, MA; Portero, M; Pamplona, R; Ferrer, I

    Redox proteomic profiling of neuroketal-adducted proteins in human brain: Regional vulnerability at middle age increases in the elderly

    FREE RADICAL BIOLOGY AND MEDICINE 95 1-15. .

    [doi:10.1016/j.freeradbiomed.2016.02.034]

  • Jové M; Maté I; Naudí A; Mota-Martorell N; Portero-Otín M; De la Fuente M; Pamplona R

    Human Aging Is a Metabolome-related Matter of Gender

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 71 578-585. .

    [doi:10.1093/gerona/glv074]

  • Pardo, L; Schluter, A; Valor, LM; Barco, A; Giralt, M; Golbano, A; Hidalgo, J; Jia, PL; Zhao, ZM; Jove, M; Portero-Otin, M; Ruiz, M; Gimenez-Llort, L; Masgrau, R; Pujol, A; Galea, E

    Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury

    Glia 64 853-874. .

    [doi:10.1002/glia.22969]

  • Moreno-Navarrete, JM; Jove, M; Ortega, F; Xifra, G; Ricart, W; Obis È; Pamplona, R; Portero-Otin, M; Fernandez-Real, JM

    Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity

    Diabetologia 59 822-832. .

    [doi:10.1007/s00125-016-3863-1]

  • Cacabelos, D; Ayala, V; Granado-Serrano, AB; Jove, M; Torres, P; Boada, J; Cabre, R; Ramirez-Nunez, O; Gonzalo, H; Soler-Cantero, A; Serrano, JCE; Bellmunt, MJ; Romero, MP; Motilva, MJ; Nonaka, T; Hasegawa, M; Ferrer, I; Pamplona, R; Portero-Otin, M

    Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis

    NEUROBIOLOGY OF DISEASE 88 148-160. .

    [doi:10.1016/j.nbd.2016.01.007]

  • Eritja, N; Arjo, G; Santacana, M; Gatius, S; Ramirez-Nunez, O; Arcal, L; Serrano, JCE; Pamplona, R; Dolcet, X; Pinol, C; Christou, P; Matias-Guiu, X; Portero-Otin, M

    Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1862 526-535. .

    [doi:10.1016/j.bbadis.2016.01.018]

  • Cacabelos, D; Ramirez-Nunez, O; Granado-Serrano, AB; Torres, P; Ayala, V; Moiseeva, V; Povedano, M; Ferrer, I; Pamplona, R; Portero-Otin, M; Boada, J

    Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS

    Acta neuropathologica communications 4 3-3. .

    [doi:10.1186/s40478-015-0271-6]

  • Nogareda C; Moreno JA; Angulo E; Sandmann G; Portero M; Capell T; Zhu C; Christou P

    Carotenoid-enriched transgenic corn delivers bioavailable carotenoids to poultry and protects them against coccidiosis

    PLANT BIOTECHNOLOGY JOURNAL 14 160-168. .

    [doi:10.1111/pbi.12369]

  • Fernandez-Real JM; Serino M; Blasco G; Puig J; Daunis-I-Estadella J; Ricart W; Burcelin R; Fernández-Aranda F; Portero-Otin M

    Gut Microbiota Interacts With Brain Microstructure and Function

    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 100 4505-4513. .

    [doi:10.1210/jc.2015-3076]

Proyectos

  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • Doctorat Industrial (DI 2015)
  • ESTRES CELULAR Y DESLOCALIZACION DE FACTORES TRANSCRIPCIONALES EN LA FISIOPATOLOGIA DE LA ELA
  • Gut microbiota profile after consumption of a patented fiber formulation
  • Pla d'Impuls de Transferència Tecnològica de NUTREN (UdL)
  • MECANISMOS DE SENESCENCIA CELULAR BASADOS EN EL ESTRES OXIDATIVO EN LA PATOGENIA DE LA ESCLEROSIS LATERAL AMIOTROFICA
  • Prototipatge i proves de concepte en el sistema expert Diagnòstic Molecular Dietari
  • Transferencia orgaular autóloga como medidad terapéutica frente a la senescencia celular
  • ENVEJECIMIENTO CELULAR COMO MECANISMO PATOGENICOEN ESCLEROSIS LATERAL AMIOTROFICA: RELACION ENTRE PEROXIDACION LIPIDICA, AUTOFAGIA Y BIOGENESIS MITOCONDRIAL