Directorio de personas
Joaquim Ros Salvador

Joaquim Ros Salvador

Grado: Doctor/a

973 702 275
joaquim.ros(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/ABG-7487-2020

Grupos

Publicaciones

  • Pazos-Gil, M; Medina-Carbonero, M; Sanz-Alcázar, A; Portillo-Carrasquer, M; Oliveira-Jorge, L; Hernández, G; Sánchez, M; Delaspre, F; Cabiscol, E; Ros, J; Tamarit, J

    Pathological frataxin deficiency in mice causes tissue-specific alterations in iron homeostasis

    iScience 29 -. .

    [doi:10.1016/j.isci.2025.114625]

  • Mengual, R; Bobo-Jiménez, V; Rodríguez, C; Lapresa, R; García-Rodríguez, D; Jiménez-Blasco, D; Cabiscol, E; Ros, J; Delgado-Esteban, M; Bolaños, JP; Almeida, A

    Endogenous mitochondrial hydrogen peroxide regulates neurogenesis during cortical development

    Redox Biology 88 103940-103940. .

    [doi:10.1016/j.redox.2025.103940]

  • Sanz-Alcázar A; Britti E; Delaspre F; Medina-Carbonero M; Pazos-Gil M; Tamarit J; Ros J; Cabiscol E

    Correction: Mitochondrial impairment, decreased Sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich ataxia models.

    Cellular And Molecular Life Sciences 82 428-428. .

    [doi:10.1007/s00018-025-05948-7]

  • Portillo-Carrasquer M; Sanz-Alcázar A; Delaspre F; Pazos-Gil M; Oliveira-Jorge L; Vergara C; Rodríguez-Pascau L; Pizcueta P; Tamarit J; Ros J; Cabiscol E

    Leriglitazone improves iron homeostasis and ferroptotic markers in frataxin-deficient dorsal root ganglia neurons.

    BIOMEDICINE & PHARMACOTHERAPY 192 118553-118553. .

    [doi:10.1016/j.biopha.2025.118553]

  • Sanz-Alcázar A; Portillo-Carrasquer M; Delaspre F; Pazos-Gil M; Tamarit J; Ros J; Cabiscol E

    Corrigendum to "Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3ß in the impairment of the NRF2 response" [Redox Biol. 76 (2024) 103339].

    Redox Biology 82 103583-103583. .

    [doi:10.1016/j.redox.2025.103583]

  • Sanz-Alcázar, A; Portillo-Carrasquer, M; Delaspre, F; Pazos-Gil, M; Tamarit, J; Ros, J; Cabiscol, E

    Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3ß in the impairment of the NRF2 response

    Redox Biology 76 103339-103339. .

    [doi:10.1016/j.redox.2024.103339]

  • Alemany-Perna B; Tamarit J; Cabiscol E; Ros J

    Reply to: "Calcitriol in Friedreich Ataxia".

    MOVEMENT DISORDERS 39 1654-1655. .

    [doi:10.1002/mds.29971]

  • Alemany-Perna, B; Tamarit, J; Cabiscol, E; Delaspre, F; Miguela, A; Huertas-Pons, JM; Quiroga-Varela, A; Ruiz, MM; Dominguez, DL; Torrenta, L; Genis, D; Ros, J

    Calcitriol Treatment Is Safe and Increases Frataxin Levels in Friedreich Ataxia Patients

    MOVEMENT DISORDERS 39 1099-1108. .

    [doi:10.1002/mds.29808]

  • Sanz-Alcázar A; Britti E; Delaspre F; Medina-Carbonero M; Pazos-Gil M; Tamarit J; Ros J; Cabiscol E

    Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models.

    Cellular And Molecular Life Sciences 81 12-12. .

    [doi:10.1007/s00018-023-05064-4]

  • Medina-Carbonero, M; Sanz-Alcázar, A; Britti, E; Delaspre, F; Cabiscol, E; Ros, J; Tamarit, J

    Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations.

    Cellular And Molecular Life Sciences 79 74-74. .

    [doi:10.1007/s00018-021-04100-5]

  • Tamarit J; Britti E; Delaspre F; Medina-Carbonero M; Sanz-Alcázar A; Cabiscol E; Ros J

    Mitochondrial iron and calcium homeostasis in Friedreich ataxia.

    IUBMB LIFE 73 543-553. .

    [doi:10.1002/iub.2457]

  • Britti E; Delaspre F; Sanz A; Medina-Carbonero M; Llovera M; Purroy R; Mincheva-Tasheva S; Tamarit J; Ros J

    Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia.

    BIOCHEMICAL JOURNAL 478 1-20. .

    [doi:10.1042/BCJ20200331]

Proyectos

  • Pre-clinical assessment of protein replacement therapy in the central nervous system of Friedreich’s ataxia mouse models
  • Uncovering the function of a conserved site in eukaryotic frataxins.
  • Desarrollo de la leriglitazona para el Síndrome de Rett y trastornos relacionados
  • Mecanismos de disfuncion mitocondrial y nuevas estrategias terapéuticas en modelos celulares y animales de Ataxia de Friedreich
  • Nuevo fármaco dirigido a la Ataxia de Friedreich
  • MithrAtaxia: Validació en laboratori dels efects protectors de mithramycin A por un us terapeutic en Ataxia de Friedreich
  • Targeting mitochondria in Friedreich Ataxia: molecular mechanisms and therapeutic approaches
  • Búsqueda de nuevas indicaciones terapéuticas en el ámbito de enfermedades neurodegenerativas y mitocondriales para el compuesto PPAR gamma agonista MIN-102
  • Effect of vitamin D in frataxin-deficient DRG neurons from rat and iPS cells obtained from FA patients
  • MODELOS CELULARES DE ATAXIA DE FRIEDREICH: BASES MOLECULARES DE LA PATOLOGIA E IDENTIFICACION DE BIOMARCADORES Y COMPUESTOS CON POTENCIAL TERAPEUTICO
  • Modelos celulares de ataxia de Friedreich: bases moleculares de la patología e identificación de biomarcadores y compuestos con potencial terapéutico
  • PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES