Joaquim Ros Salvador
Grado: Doctor/a
973 702 275
joaquim.ros(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/ABG-7487-2020
Publicaciones
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Britti, E; Delaspre, F; Tamarit, J; Ros, J
Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na + /Ca 2+ Exchanger, NCLX, and Apoptosis.
NEUROCHEMICAL RESEARCH 46 108-119. .
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Rodríguez-Pascau L; Britti E; Calap-Quintana P; Dong YN; Vergara C; Delaspre F; Medina M; Tamarit J; Pallardó FV; Gonzalez-Cabo P; Ros J; Lynch DR; Martinell M; Pizcueta P
PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia.
NEUROBIOLOGY OF DISEASE 148 105162-105162. .
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Rodríguez Colman MJ; Ros J; Cabiscol E
Mitochondrial Localization of the Yeast Forkhead Factor Hcm1.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 1-11. .
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Purroy, R; Medina-Carbonero, M; Ros, J; Tamarit, J
Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase.
Redox Biology 32 101520-101520. .
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Britti, E; Ros, J; Esteras, N; Abramov, AY
Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death.
Cell Calcium 86 102150-102150. .
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Elena Britti; Noemi Esteras Gallego; Joaquim Ros; Andrey Y. Abramov
Mitochondrial Calcium Deregulation in Tau K18-Treated Cortical Neurons and Astrocytes
BIOPHYSICAL JOURNAL 116 270-271. .
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Britti, Elena; Delaspre, Fabien; Tamarit, Jordi; Ros, Joaquim
Mitochondrial calcium signalling and neurodegenerative diseases
Neuronal Signaling 2 20180061-20180061. .
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Fernandez-Fernandez, S; Bobo-Jimenez, V; Requejo-Aguilar, R; Gonzalez-Fernandez, S; Resch, M; Carabias-Carrasco, M; Ros, J; Almeida, A; Bolaños JP
Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function
Redox Biology 19 52-61. .
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Alsina, D; Purroy, R; Ros, J; Tamarit, J
Iron in Friedreich Ataxia: A Central Role in the Pathophysiology or an Epiphenomenon?
PHARMACEUTICALS 11 -. .
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Britti, E; Delaspre, F; Mincheva, S; Llovera, M; Tamarit, J; Ros, J
Calcitriol as a supplement for Friedreich ataxia
FEBS Open Bio 8 213-213. .
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Lledos, RP; Ros, J; Tamarit, J
Alterations in mitochondrial multimeric dehydrogenase complexes in a cardiac model of Friedreich ataxia
FEBS Open Bio 8 91-92. .
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Alsina, D; Ros, J; Tamarit, J
Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast
Redox Biology 14 131-141. .
Proyectos
- Pre-clinical assessment of protein replacement therapy in the central nervous system of Friedreich’s ataxia mouse models
- Uncovering the function of a conserved site in eukaryotic frataxins.
- Desarrollo de la leriglitazona para el Síndrome de Rett y trastornos relacionados
- Mecanismos de disfuncion mitocondrial y nuevas estrategias terapéuticas en modelos celulares y animales de Ataxia de Friedreich
- Nuevo fármaco dirigido a la Ataxia de Friedreich
- MithrAtaxia: Validació en laboratori dels efects protectors de mithramycin A por un us terapeutic en Ataxia de Friedreich
- Targeting mitochondria in Friedreich Ataxia: molecular mechanisms and therapeutic approaches
- Búsqueda de nuevas indicaciones terapéuticas en el ámbito de enfermedades neurodegenerativas y mitocondriales para el compuesto PPAR gamma agonista MIN-102
- Effect of vitamin D in frataxin-deficient DRG neurons from rat and iPS cells obtained from FA patients
- MODELOS CELULARES DE ATAXIA DE FRIEDREICH: BASES MOLECULARES DE LA PATOLOGIA E IDENTIFICACION DE BIOMARCADORES Y COMPUESTOS CON POTENCIAL TERAPEUTICO
- Modelos celulares de ataxia de Friedreich: bases moleculares de la patología e identificación de biomarcadores y compuestos con potencial terapéutico
- PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES