Directorio de personas
Manuel Portero Otin

Manuel Portero Otin

Grado: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Grupos

Publicaciones

  • Quiles, Jose L.; Pamplona, Reinald; Carmen Ramirez-Tortosa, M.; Naudi, Alba; Portero-Otin, Manuel; Araujo-Nepomuceno, Eduardo; Lopez-Frias, Magdalena; Battino, Maurizio; Ochoa, Julio J.

    Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart.

    MECHANISMS OF AGEING AND DEVELOPMENT 131 38-47. .

    [doi:10.1016/j.mad.2009.11.004]

  • Kichev, Anton; Ilieva, Ekaterina V.; Pinol-Ripoll, Gerard; Podlesniy, Petar; Ferrer, Isidro; Portero-Otin, Manuel; Pamplona, Reinald; Espinet, Carme

    Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.

    AMERICAN JOURNAL OF PATHOLOGY 175 2574-2585. .

    [doi:10.2353/ajpath.2009.090018]

  • Negre-Salvayre, Anne; Salvayre, Robert; Auge, Nathalie; Pamplona, Reinald; Portero-Otin, Manuel

    Hyperglycemia and glycation in diabetic complications.

    ANTIOXIDANTS & REDOX SIGNALING 11 3071-3109. .

    [doi:10.1089/ars.2009.2484]

  • Serrano, Jose; Jove, Mariona; Boada, Jordi; Josep Bellmunt, Maria; Pamplona, Reinald; Portero-Otin, Manuel

    Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays.

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 388 443-449. .

    [doi:10.1016/j.bbrc.2009.08.041]

  • Erauskin, JL; Fourcade, S; Ferrer, I; Pamplona, R; Portero-Otin, M; Pujol, A

    ANTIOXIDANTS AS A THERAPEUTIC HOPE FOR X-LINKED ADRENOLEUKODYSTROPHY

    Glia 57 100-101. .

  • Caro, Pilar; Gomez, Jose; Sanchez, Ines; Garcia, Ruben; Lopez-Torres, Monica; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo

    Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver.

    Biogerontology 10 579-592. .

    [doi:10.1007/s10522-008-9200-4]

  • Gomez, Jose; Caro, Pilar; Sanchez, Ines; Naudi, Alba; Jove, Mariona; Portero-Otin, Manuel; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

    Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart.

    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 41 309-321. .

    [doi:10.1007/s10863-009-9229-3]

  • Martinez, Anna; Carmona, Margarita; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Ferrer, Isidre

    Type-dependent oxidative damage in frontotemporal lobar degeneration: cortical astrocytes are targets of oxidative damage (vol 67, pg 1122, 2008)

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 68 112-112. .

  • Martinez, Anna; Carmona, Margarita; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Ferrer, Isidre

    Type-dependent oxidative damage in frontotemporal lobar degeneration: cortical astrocytes are targets of oxidative damage.

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 67 1122-1136. .

    [doi:10.1097/NEN.0b013e31818e06f3]

  • Pamplona, Reinald; Naudi, Alba; Gavin, Rosalina; Pastrana, Miguel A.; Sajnani, Gustavo; Ilieva, Ekaterina V.; Antonio del Rio, Jose; Portero-Otin, Manuel; Ferrer, Isidre; Requena, Jesus R.

    Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease.

    FREE RADICAL BIOLOGY AND MEDICINE 45 1159-1166. .

    [doi:10.1016/j.freeradbiomed.2008.07.009]

  • Fourcade, Stephane; Lopez-Erauskin, Jone; Galino, Jorge; Duval, Carine; Naudi, Alba; Jove, Mariona; Kemp, Stephan; Villarroya, Francesc; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel; Pujol, Aurora

    Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.

    HUMAN MOLECULAR GENETICS 17 1762-1773. .

    [doi:10.1093/hmg/ddn085]

  • Caro, Pilar; Gomez, Jose; Lopez-Torres, Monica; Sanchez, Ines; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo

    Effect of every other day feeding on mitochondrial free radical production and oxidative stress in mouse liver.

    REJUVENATION RESEARCH 11 621-629. .

    [doi:10.1089/rej.2008.0704]

Proyectos

  • SEED-ALS: Synergizing Efforts to Develop and Accelerate Breakthroughs in ALS Research
  • Natural microbicides from rice against current and emerging infectious diseases
  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • Comprehensive Roadmap and Preclinical Evaluation of Antisense Oligonucleotides (ASOs) Regulatory Development and Toxicological Assessment for ALS Treatment
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig