
Manuel Portero Otin
Grado: Doctor/a
973 702 408
manuel.portero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/B-7122-2009
Grupos
Publicaciones
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Hiona, Asimina; Sanz, Alberto; Kujoth, Gregory C.; Pamplona, Reinald; Seo, Arnold Y.; Hofer, Tim; Someya, Shinichi; Miyakawa, Takuya; Nakayama, Chie; Samhan-Arias, Alejandro K.; Servais, Stephane; Barger, Jamie L.; Portero-Otin, Manuel; Tanokura, Masaru; Prolla, Tomas A.; Leeuwenburgh, Christiaan
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.
PLOS ONE 5 -. .
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Casos, Kelly; Zaragoza, Maria C.; Zarkovic, Neven; Zarkovic, Kamelija; Andrisic, Luka; Portero-Otin, Manuel; Cacabelos, Daniel; Mitjavila, Maria T.
A fish-oil-rich diet reduces vascular oxidative stress in apoE(-/-) mice.
FREE RADICAL RESEARCH 44 821-829. .
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Jove, Mariona; Serrano, Jose C. E.; Bellmunt, Maria Josep; Cassanye, Anna; Angles, Neus; Reguant, Jordi; Morello, Jose R.; Pamplona, Reinald; Portero-Otin, Manuel
When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts.
LIPIDS IN HEALTH AND DISEASE 9 65-65. .
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Serrano, Jose; Cipak, Ana; Boada, Jordi; Gonzalo, Hugo; Cacabelos, Daniel; Cassanye, Anna; Pamplona, Reinald; Zarkovic, Neven; Portero-Otin, Manuel
Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects.
ACTA BIOCHIMICA POLONICA 57 193-198. .
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Sanz, Alberto; Soikkeli, Mikko; Portero-Otin, Manuel; Wilson, Angela; Kemppainen, Esko; McIlroy, George; Ellila, Simo; Kemppainen, Kia K.; Tuomela, Tea; Lakanmaa, Matti; Kiviranta, Essi; Stefanatos, Rhoda; Dufour, Eric; Hutz, Bettina; Naudi, Alba; Jove, Mariona; Zeb, Akbar; Vartiainen, Suvi; Matsuno-Yagi, Akemi; Yagi, Takao; Rustin, Pierre; Pamplona, Reinald; Jacobs, Howard T.
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 9105-9110. .
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Fourcade, Stephane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudi, Alba; Portero-Otin, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona, Reinald; Aubourg, Patrick; Pujol, Aurora
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
HUMAN MOLECULAR GENETICS 19 2005-2014. .
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Ilieva, Ekaterina V.; Naudi, Alba; Kichev, Anton; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel
Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease.
FREE RADICAL BIOLOGY AND MEDICINE 48 1302-1310. .
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Naudí A; Jové M; Ayala V; Portero-Otín M; Pamplona R
Glicación de proteínas mitocondriales, estrés oxidativo y envejecimiento.
Revista espanola de geriatria y gerontologia 45 156-166. .
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Martinez, Anna; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidre
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.
BRAIN PATHOLOGY 20 281-297. .
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Muntane, Gerard; Janue, Anna; Fernandez, Nuria; Odena, Maria Antonia; Oliveira, Eliandre; Boluda, Susana; Portero-Otin, Manuel; Naudi, Alba; Boada, Jordi; Pamplona, Reinald; Ferrer, Isidre
Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids.
NEUROCHEMISTRY INTERNATIONAL 56 318-328. .
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Terni, Beatrice; Boada, Jordi; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidro
Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.
BRAIN PATHOLOGY 20 222-233. .
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Fernandez, Liana Lisboa; Carmona, Marga; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Schroeder, Nadja; Ferrer, Isidro
Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice.
Journal Of Alzheimers Disease 19 1069-1080. .
Proyectos
- SEED-ALS: Synergizing Efforts to Develop and Accelerate Breakthroughs in ALS Research
- Natural microbicides from rice against current and emerging infectious diseases
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Targeting cryptic exons as biomarkers and ALS therapy
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- Comprehensive Roadmap and Preclinical Evaluation of Antisense Oligonucleotides (ASOs) Regulatory Development and Toxicological Assessment for ALS Treatment
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Determinació de components bioactius derivats de la microbiota mitjançant micromostreig