Directorio de personas
Reinald Pamplona Gras

Reinald Pamplona Gras

Grado: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Grupos

Publicaciones

  • Lambert, AJ; Portero-Otin, M; Pamplona, R; Merry, BJ

    Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria.

    MECHANISMS OF AGEING AND DEVELOPMENT 125 529-538. .

    [doi:10.1016/j.mad.2004.06.002]

  • Venditti, P; De Rosa, R; Portero-Otin, M; Pamplona, R; Di Meo, S

    Cold-induced hyperthyroidism produces oxidative damage in rat tissues and increases susceptibility to oxidants.

    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36 1319-1331. .

    [doi:10.1016/j.biocel.2003.11.005]

  • Pamplona, R; Portero-Otin, M; Sanz, A; Requena, J; Barja, G

    Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain.

    Experimental Gerontology 39 725-733. .

    [doi:10.1016/j.exger.2004.01.006]

  • Mew, TW; Cottyn, B; Pamplona, R; Barrios, H; Li, XM; Chen, ZY; Lu, F; Nilpanit, N; Arunyanart, P; Kim, PV; Du, PV

    Applying rice seed-associated antagonistic bacteria to manage rice sheath blight in developing countries

    Plant Disease 88 557-564. .

    [doi:10.1094/PDIS.2004.88.5.557]

  • Portero-Otin, M; Bellmunt, MJ; Requena, JR; Pamplona, R

    Protein modification by advanced Maillard adducts can be modulated by dietary polyunsaturated fatty acids.

    Biochemical Society Transactions 31 1403-1405. .

    [doi:10.1042/bst0311403]

  • Echtay, KS; Esteves, TC; Pakay, JL; Jekabsons, MB; Lambert, AJ; Portero-Otin, M; Pamplona, R; Vidal-Puig, AJ; Wang, S; Roebuck, SJ; Brand, MD

    A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.

    Embo Journal 22 4103-4110. .

    [doi:10.1093/emboj/cdg412]

  • Ruiz, MC; Portero-Otin, M; Pamplona, R; Requena, JR; Prat, J; Lafarga, MA; Borras, M; Bellmunt, MJ

    Chemical and immunological characterization of oxidative nonenzymatic protein modifications in dialysis fluids.

    Peritoneal Dialysis International 23 23-32. .

  • Brand, MD; Pamplona, R; Portero-Otin, M; Requena, JR; Roebuck, SJ; Buckingham, JA; Clapham, JC; Cadenas, S

    Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

    BIOCHEMICAL JOURNAL 368 597-603. .

    [doi:10.1042/BJ20021077]

  • Pamplona, R; Portero-Otin, M; Requena, J; Gredilla, R; Barja, G

    Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls.

    MECHANISMS OF AGEING AND DEVELOPMENT 123 1437-1446. .

    [doi:10.1016/S0047-6374(02)00076-3]

  • Portero-Otin, M; Pamplona, R; Bellmunt, MJ; Ruiz, MC; Prat, J; Salvayre, R; Negre-Salvayre, A

    Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

    Diabetes 51 1535-1542. .

    [doi:10.2337/diabetes.51.5.1535]

  • Pamplona R; Barja G; PORTERO OTIN, MANUEL

    Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: a homeoviscous-longevity adaptation?

    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 959 475-490. .

  • Pamplona, R; Portero-Otin, M; Bellmunt, MJ; Gredilla, R; Barja, G

    Aging increases N(epsilon)-(carboxymethyl)lysine and caloric restriction decreases N(epsilon)-(carboxyethyl)lysine and N(epsilon)-(malondialdehyde)lysine in rat heart mitochondrial proteins

    FREE RADICAL RESEARCH 36 47-54. .

    [doi:10.1080/10715760290001281]

Proyectos

  • Insight into the role of lipids in frontotemporal dementia: uncovering pathophysiological alterations and biomarker discovery opportunities.
  • Metabolismo de eter lípidos y envejecimiento humano
  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement