Directorio de personas
Reinald Pamplona Gras

Reinald Pamplona Gras

Grado: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Grupos

Publicaciones

  • Hiona, Asimina; Sanz, Alberto; Kujoth, Gregory C.; Pamplona, Reinald; Seo, Arnold Y.; Hofer, Tim; Someya, Shinichi; Miyakawa, Takuya; Nakayama, Chie; Samhan-Arias, Alejandro K.; Servais, Stephane; Barger, Jamie L.; Portero-Otin, Manuel; Tanokura, Masaru; Prolla, Tomas A.; Leeuwenburgh, Christiaan

    Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.

    PLOS ONE 5 -. .

    [doi:10.1371/journal.pone.0011468]

  • Pamplona R

    Restricción dietaria y envejecimiento: ¿una cuestión de calorías?

    Revista espanola de geriatria y gerontologia 45 232-238. .

    [doi:10.1016/j.regg.2010.05.001]

  • Jove, Mariona; Serrano, Jose C. E.; Bellmunt, Maria Josep; Cassanye, Anna; Angles, Neus; Reguant, Jordi; Morello, Jose R.; Pamplona, Reinald; Portero-Otin, Manuel

    When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts.

    LIPIDS IN HEALTH AND DISEASE 9 65-65. .

    [doi:10.1186/1476-511X-9-65]

  • Serrano, Jose; Cipak, Ana; Boada, Jordi; Gonzalo, Hugo; Cacabelos, Daniel; Cassanye, Anna; Pamplona, Reinald; Zarkovic, Neven; Portero-Otin, Manuel

    Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects.

    ACTA BIOCHIMICA POLONICA 57 193-198. .

  • Sanz, Alberto; Soikkeli, Mikko; Portero-Otin, Manuel; Wilson, Angela; Kemppainen, Esko; McIlroy, George; Ellila, Simo; Kemppainen, Kia K.; Tuomela, Tea; Lakanmaa, Matti; Kiviranta, Essi; Stefanatos, Rhoda; Dufour, Eric; Hutz, Bettina; Naudi, Alba; Jove, Mariona; Zeb, Akbar; Vartiainen, Suvi; Matsuno-Yagi, Akemi; Yagi, Takao; Rustin, Pierre; Pamplona, Reinald; Jacobs, Howard T.

    Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 9105-9110. .

    [doi:10.1073/pnas.0911539107]

  • Ilieva, Ekaterina V.; Naudi, Alba; Kichev, Anton; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel

    Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease.

    FREE RADICAL BIOLOGY AND MEDICINE 48 1302-1310. .

    [doi:10.1016/j.freeradbiomed.2010.02.006]

  • Fourcade, Stephane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudi, Alba; Portero-Otin, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona, Reinald; Aubourg, Patrick; Pujol, Aurora

    Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.

    HUMAN MOLECULAR GENETICS 19 2005-2014. .

    [doi:10.1093/hmg/ddq082]

  • Naudí A; Jové M; Ayala V; Portero-Otín M; Pamplona R

    Glicación de proteínas mitocondriales, estrés oxidativo y envejecimiento.

    Revista espanola de geriatria y gerontologia 45 156-166. .

    [doi:10.1016/j.regg.2010.02.001]

  • Martinez, Anna; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidre

    Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.

    BRAIN PATHOLOGY 20 281-297. .

    [doi:10.1111/j.1750-3639.2009.00326.x]

  • Quiles, Jose L.; Pamplona, Reinald; Carmen Ramirez-Tortosa, M.; Naudi, Alba; Portero-Otin, Manuel; Araujo-Nepomuceno, Eduardo; Lopez-Frias, Magdalena; Battino, Maurizio; Ochoa, Julio J.

    Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart.

    MECHANISMS OF AGEING AND DEVELOPMENT 131 38-47. .

    [doi:10.1016/j.mad.2009.11.004]

  • Muntane, Gerard; Janue, Anna; Fernandez, Nuria; Odena, Maria Antonia; Oliveira, Eliandre; Boluda, Susana; Portero-Otin, Manuel; Naudi, Alba; Boada, Jordi; Pamplona, Reinald; Ferrer, Isidre

    Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids.

    NEUROCHEMISTRY INTERNATIONAL 56 318-328. .

    [doi:10.1016/j.neuint.2009.10.015]

  • Terni, Beatrice; Boada, Jordi; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidro

    Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.

    BRAIN PATHOLOGY 20 222-233. .

    [doi:10.1111/j.1750-3639.2009.00266.x]

Proyectos

  • Insight into the role of lipids in frontotemporal dementia: uncovering pathophysiological alterations and biomarker discovery opportunities.
  • Metabolismo de eter lípidos y envejecimiento humano
  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement