Directorio de personas
Reinald Pamplona Gras

Reinald Pamplona Gras

Grado: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Publicaciones

  • Galea, Elena; Launay, Nathalie; Portero-Otin, Manuel; Ruiz, Montserrat; Pamplona, Reinald; Aubourg, Patrick; Ferrer, Isidre; Pujol, Aurora

    Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1822 1475-1488. .

    [doi:10.1016/j.bbadis.2012.02.005]

  • Aso, Ester; Lomoio, Selene; Lopez-Gonzalez, Irene; Joda, Laura; Carmona, Margarita; Fernandez-Yaguee, Nuria; Moreno, Jesus; Juves, Salvador; Pujol, Aurora; Pamplona, Reinald; Portero-Otin, Manuel; Martin, Virginia; Diaz, Mario; Ferrer, Isidro

    Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease

    BRAIN PATHOLOGY 22 636-653. .

    [doi:10.1111/j.1750-3639.2011.00560.x]

  • Soler-Cantero, Arantza; Jove, Mariona; Cacabelos, Daniel; Boada, Jordi; Naudi, Alba; Romero, Maria-Paz; Cassanye, Anna; Serrano, Jose C. E.; Arola, Lluis; Valls, Josep; Josep Bellmunt, Maria; Prat, Joan; Pamplona, Reinald; Portero-Otin, Manuel; Motilva, Maria-Jose

    Plant-Derived Phenolics Inhibit the Accrual of Structurally Characterised Protein and Lipid Oxidative Modifications

    PLOS ONE 7 -. .

    [doi:10.1371/journal.pone.0043308]

  • Sanchez-Roman, Ines; Gomez, Alexia; Perez, Irene; Sanchez, Carlota; Suarez, Henar; Naudi, Alba; Jove, Mariona; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

    Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria

    Biogerontology 13 399-411. .

    [doi:10.1007/s10522-012-9384-5]

  • Das, A.; Pushparaj, C.; Bahi, N.; Sorolla, A.; Herreros, J.; Pamplona, R.; Vilella, R.; Matias-Guiu, X.; Marti, R. M.; Canti, C.

    Functional expression of voltage-gated calcium channels in human melanoma

    PIGMENT CELL & MELANOMA RESEARCH 25 200-212. .

    [doi:10.1111/j.1755-148X.2012.00978.x]

  • Naudi, Alba; Jove, Mariona; Ayala, Victoria; Cassanye, Anna; Serrano, Jose; Gonzalo, Hugo; Boada, Jordi; Prat, Joan; Portero-Otin, Manuel; Pamplona, Reinald

    Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress

    EXPERIMENTAL DIABETES RESEARCH 2012 696215-696215. .

    [doi:10.1155/2012/696215]

  • Grimstad, Tore; Bjorndal, Bodil; Cacabelos, Daniel; Aasprong, Ole Gunnar; Janssen, Emiel A. M.; Omdal, Roald; Svardal, Asbjorn; Hausken, Trygve; Bohov, Pavol; Portero-Otin, Manuel; Pamplona, Reinald; Berge, Rolf K.

    Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats

    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 47 49-58. .

    [doi:10.3109/00365521.2011.634025]

  • Sanchez-Roman, Ines; Gomez, Alexia; Gomez, Jose; Suarez, Henar; Sanchez, Carlota; Naudi, Alba; Ayala, Victoria; Portero-Otin, Manuel; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

    Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart.

    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 43 699-708. .

    [doi:10.1007/s10863-011-9389-9]

  • Galino, Jorge; Ruiz, Montserrat; Fourcade, Stephane; Schlueter, Agatha; Lopez-Erauskin, Jone; Guilera, Cristina; Jove, Mariona; Naudi, Alba; Garcia-Arumi, Elena; Andreu, Antoni L.; Starkov, Anatoly A.; Pamplona, Reinald; Ferrer, Isidre; Portero-Otin, Manuel; Pujol, Aurora

    Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy.

    ANTIOXIDANTS & REDOX SIGNALING 15 2095-2107. .

    [doi:10.1089/ars.2010.3877]

  • Pamplona, Reinald; Costantini, David

    Molecular and structural antioxidant defenses against oxidative stress in animals.

    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 301 843-863. .

    [doi:10.1152/ajpregu.00034.2011]

  • Pamplona, Reinald; Barja, Gustavo

    An evolutionary comparative scan for longevity-related oxidative stress resistance mechanisms in homeotherms.

    Biogerontology 12 409-435. .

    [doi:10.1007/s10522-011-9348-1]

  • Ayala, Victoria; Belen Granado-Serrano, Ana; Cacabelos, Daniel; Naudi, Alba; Ilieva, Ekaterina V.; Boada, Jordi; Caraballo-Miralles, Victor; Llado, Jeronia; Ferrer, Isidro; Pamplona, Reinald; Portero-Otin, Manuel

    Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS.

    ACTA NEUROPATHOLOGICA 122 259-270. .

    [doi:10.1007/s00401-011-0850-y]

Proyectos

  • Insight into the role of lipids in frontotemporal dementia: uncovering pathophysiological alterations and biomarker discovery opportunities.
  • Metabolismo de eter lípidos y envejecimiento humano
  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement