Directorio de personas
Alba Sansa Zaragoza

Alba Sansa Zaragoza

Grado: Máster

970702407
asansa(ELIMINAR)@irblleida.cat

Publicaciones

  • Sansa A; Hidalgo I; Miralles MP; de la Fuente S; Perez-Garcia MJ; Munell F; Soler RM; Garcera A

    Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons.

    Acta neuropathologica communications 9 122-122. .

    [doi:10.1186/s40478-021-01223-5]

  • Sansa A; de la Fuente S; Comella JX; Garcera A; Soler RM

    Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons.

    NEUROBIOLOGY OF DISEASE 155 105366-105366. .

    [doi:10.1016/j.nbd.2021.105366]

  • de la Fuente, S; Sansa, A; Hidalgo, I; Vivancos, N; Romero-Guevara, R; Garcera, A; Soler, RM

    Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.

    CELL DEATH & DISEASE 11 487-487. .

    [doi:10.1038/s41419-020-2688-5]

  • de la Fuente, S; Sansa, A; Periyakaruppiah, A; Garcera, A; Soler, RM

    Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice

    MOLECULAR NEUROBIOLOGY 56 4414-4427. .

    [doi:10.1007/s12035-018-1379-z]

Proyectos

  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • Analysis of the beneficial effects of calpain inhibitors treatment and combined therapies on Spinal Muscular Atrophy
  • Nuevas terapias para el tratamiento de la Atrofia Muscular Espinal: inhibidores de la calpaina y células madre mesenquimales modificadas
  • Desarrollo de nuevas estrategias terapéuticas para el tratamiento de la atrofia muscular espinal: regulación de la autofagia y las vías de señalización intracelular