Drosophila disease models and (epi)genetic analysis
Our research group embodies a multidisciplinary approach, encompassing diverse research lines that delve into both basic and translational research. Our work primarily revolves around two key research areas
- Utilizing Drosophila as a model organism to delve into the genetic and biological underpinnings of human diseases, with a particular emphasis on metastatic colorectal cancer.
- Delving into the comprehensive characterization of genetic and epigenetic alterations in complex traits, discerning their involvement in disease susceptibility and progression.
Featured publications
Adams, J; Casali, A; Campbell, K
Methods to Generate and Assay for Distinct Stages of Cancer Metastasis in Adult Drosophila melanogaster.
Methods in Molecular Biology 2179 161-170. .
Campbell, K; Rossi, F; Adams, J; Pitsidianaki, I; Barriga, FM; Garcia-Gerique, L; Batlle, E; Casanova, J; Casali, A
Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors
Nature Communications 10 2311-2311. .
