Research > Neurosciences

Molecular and developmental neurobiology

Our goal is the characterization of new molecular mechanisms involved in the formation (development) and remodelling (adult neurogenesis) of the neuronal circuits in the vertebrate nervous system. Our model are genetically modified mice and we expect that our studies will help to shed some light on or understanding of the aetiology of neurological and psychiatric disorders such as schizophrenia and the autism as well as neurodegenerative diseases such as Alzheimer’s disease, in humans. In our studies we use a wide spectrum of technical approaches, from in vivo (behaviour, mouse genetics, in utero electroporation and tissue processing and analysis), in vitro (primary tissue culture of explants or of dissociated neurons) to biochemistry and molecular biology.

Featured publication

Espinet C; Gonzalo H; Fleitas C; Menal MJ; Egea J

Oxidative Stress and Neurodegenerative Diseases: A Neurotrophic Approach

CURRENT DRUG TARGETS 16 20-30. .

[doi:10.2174/1389450116666150107153233]

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Contact information

Joaquin Egea Navarro

Joaquin Egea Navarro

Carmen Espinet Mestre

Carmen Espinet Mestre

973702250

joaquim.egea(ELIMINAR)@cmb.udl.cat

carme.espinet(ELIMINAR)@cmb.udl.cat